The m6A methyltransferase Ime4 epitranscriptionally regulates triacylglycerol metabolism and vacuolar morphology in haploid yeast cells.

doi:10.1074/jbc.M117.783761

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Article

The m6A methyltransferase Ime4 epitranscriptionally regulates triacylglycerol metabolism and vacuolar morphology in haploid yeast cells.

The Journal of biological chemistry - 18 Aug 2017

Yadav Pradeep Kumar, Rajasekharan Ram

Abstract excerpt

N6-Methyladenosine (m6A) is among the most common modifications in eukaryotic mRNA. The role of yeast m6A methyltransferase, Ime4, in meiosis and sporulation in diploid strains is very well studied, but its role in haploid strains has remained unknown. Here, with the help of an immunoblotting strategy and Ime4-GFP protein localization studies, we establish the physiological role of Ime4 in haploid cells. Our data...

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Topics

Activating Transcription Factor 2
Amino Acid Substitution
Cell Cycle Proteins
Coenzyme A Ligases
Diploidy
Epigenesis, Genetic

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Gene Deletion

Gene Expression Regulation, Fungal

Haploidy

Luminescent Proteins

Methylation

Methyltransferases

Microscopy, Electron, Scanning

Mutagenesis, Site-Directed

Mutation

Organelle Size

RNA Processing, Post-Transcriptional

Recombinant Fusion Proteins

Source

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Identifiers

PMID: 28655762
DOI: 10.1074/jbc.M117.783761
PMCID: PMC5566527

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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