Article
Functional characterization of the YmcB and YqeV tRNA methylthiotransferases of Bacillus subtilis.
Nucleic acids research - 1 Oct 2010
Anton Brian P, Russell Susan P, Vertrees Jason, Kasif Simon, Raleigh Elisabeth A, Limbach Patrick A, Roberts Richard J
Abstract excerpt
Methylthiotransferases (MTTases) are a closely related family of proteins that perform both radical-S-adenosylmethionine (SAM) mediated sulfur insertion and SAM-dependent methylation to modify nucleic acid or protein targets with a methyl thioether group (-SCH(3)). Members of two of the four known subgroups of MTTases have been characterized, typified by MiaB, which modifies N(6)-isopentenyladenosine (i(6)A) to...
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