Article
Direct response elements of BMP within the PV.1A promoter are essential for its transcriptional regulation during early Xenopus development.
PloS one - 1 Jan 2011
Lee Hyun-Shik, Lee Sung-Young, Lee Hyosang, Hwang Yoo-Seok, Cha Sang-Wook, Park Soochul, Lee Jae-Yong, Park Jae-Bong, Kim Sungchan, Park Mae Ja, Kim Jaebong
Abstract excerpt
Xvent homeobox genes encode transcription factors that repress organizer genes and are essential for dorsoventral specification during early embryogenesis in Xenopus. In contrast to the Xvent-2 gene subfamily, Xvent-1 subfamily members, including PV.1A, have been proposed as indirect targets of Bone Morphogenetic Protein-4 (BMP-4) signaling. Because PV.1A is a critical downstream mediator of, and tightly...
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