Article
Zebrafish bmp4 functions during late gastrulation to specify ventroposterior cell fates.
Developmental biology - 1 Oct 2007
Stickney Heather L, Imai Yoshiyuki, Draper Bruce, Moens Cecilia, Talbot William S
Abstract excerpt
Bone morphogenetic proteins (BMPs) are key mediators of dorsoventral patterning in vertebrates and are required for the induction of ventral fates in fish and frogs. A widely accepted model of dorsoventral patterning postulates that a morphogenetic BMP activity gradient patterns cell fates along the dorsoventral axis. Recent work in zebrafish suggests that the role of BMP signaling changes over time, with BMPs...
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