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Article

Conservation and diversification of an ancestral chordate gene regulatory network for dorsoventral patterning.

PloS one - 3 Feb 2011

Kozmikova Iryna, Smolikova Jana, Vlcek Cestmir, Kozmik Zbynek

Abstract excerpt

Formation of a dorsoventral axis is a key event in the early development of most animal embryos. It is well established that bone morphogenetic proteins (Bmps) and Wnts are key mediators of dorsoventral patterning in vertebrates. In the cephalochordate amphioxus, genes encoding Bmps and transcription factors downstream of Bmp signaling such as Vent are expressed in patterns reminiscent of those of their...

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PMID: 21304903
DOI: 10.1371/journal.pone.0014650
PMCID: PMC3033397

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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