Article
TAK1 regulates NF-ΚB and AP-1 activation in airway epithelial cells following RSV infection.
Virology - 30 Sept 2011
Dey Nilay, Liu Tianshuang, Garofalo Roberto P, Casola Antonella
Abstract excerpt
Respiratory syncytial virus (RSV) is the most common cause of epidemic respiratory diseases in infants and young children. RSV infection of airway epithelial cells induces the expression of immune/inflammatory genes through the activation of a subset of transcription factors, including Nuclear Factor-κB (NF-κB) and AP-1. In this study, we have investigated the signaling pathway leading to activation of these two...
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