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Article

Renal phosphate handling and inherited disorders of phosphate reabsorption: an update.

Pediatric nephrology (Berlin, Germany) - 1 Apr 2019

Wagner Carsten A, Rubio-Aliaga Isabel, Hernando Nati

Abstract excerpt

Renal phosphate handling critically determines plasma phosphate and whole body phosphate levels. Filtered phosphate is mostly reabsorbed by Na+-dependent phosphate transporters located in the brush border membrane of the proximal tubule: NaPi-IIa (SLC34A1), NaPi-IIc (SLC34A3), and Pit-2 (SLC20A2). Here we review new evidence for the role and relevance of these transporters in inherited disorders of renal...

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Share to Familial Hypophosphatemic Rickets
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Kidney Tubules, Proximal

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Share to Renal Tubular Transport, Inborn Errors

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Share to Sodium-Phosphate Cotransporter Proteins, Type III

Source

Identifiers

PMID: 29275531
DOI: 10.1007/s00467-017-3873-3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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