Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The roles of Na/Pi-II transporters in phosphate metabolism.

Bone - 1 Jul 2009

Segawa Hiroko, Aranami Fumito, Kaneko Ichiro, Tomoe Yuka, Miyamoto Ken-ichi

Abstract excerpt

The renal type II Na/Pi cotransporters, Na/Pi-IIa and Na/Pi-IIc, are expressed in the brush border membrane (BBM) of the renal proximal tubule cells. Because it has long been thought that Na/Pi-IIa alone can regulate the reabsorption of phosphate in the proximal renal tubules, Na/Pi-IIc has not been paid much attention by the renal research community. Recent studies, however, have identified Na/Pi-IIc mutations...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Familial Hypophosphatemic Rickets
Share to Hypercalciuria
Share to Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Phosphates

Share to Phosphoproteins

Share to Sodium-Hydrogen Exchangers

Source

Identifiers

PMID: 19232403
DOI: 10.1016/j.bone.2009.02.003

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The roles of Na/Pi-II transporters in phosphate metabolism.PMID 19232403Read ↗

Renal phosphate handling and inherited disorders of phosphate reabsorption: an update.Semantic proximity Read ↗

Sodium-dependent phosphate cotransporters: lessons from gene knockout and mutation studies.Semantic proximity Read ↗

Npt2a and Npt2c in mice play distinct and synergistic roles in inorganic phosphate metabolism and skeletal development.Semantic proximity Read ↗

[GENETIC DISORDERS OF RENAL PHOSPHATE HANDLING].Semantic proximity Read ↗

[Updates on rickets and osteomalacia: the role of NaPi-2c/SLC34A3 and hypophosphataemic rickets].Semantic proximity Read ↗

Inorganic phosphate homeostasis in sodium-dependent phosphate cotransporter Npt2b⁺/⁻ mice.Semantic proximity Read ↗

Hypophosphatemic rickets with hypercalciuria due to mutation in SLC34A3/NaPi-IIc can be masked by vitamin D deficiency and can be associated with renal calcifications.Semantic proximity Read ↗

SLC34A3 mutations in patients with hereditary hypophosphatemic rickets with hypercalciuria predict a key role for the sodium-phosphate cotransporter NaPi-IIc in maintaining phosphate homeostasis.Semantic proximity Read ↗

Relationship between sodium-dependent phosphate transporter (NaPi-IIc) function and cellular vacuole formation in opossum kidney cells.Semantic proximity Read ↗

Clinical consequences of mutations in sodium phosphate cotransporters.Semantic proximity Read ↗

Genetic diseases of renal phosphate handling.Semantic proximity Read ↗

Renal phosphate-wasting disorders.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.