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Article

HIV-2 A-subtype gp125c₂-v₃-c₃ mutations and their association with CCR5 and CXCR4 tropism.

Archives of virology - 1 Nov 2011

Dimonte Salvatore, Svicher Valentina, Salpini Romina, Ceccherini-Silberstein Francesca, Perno Carlo-Federico, Babakir-Mina Muhammed

Abstract excerpt

The early events of the HIV replication cycle involve the interaction between viral envelope glycoproteins and their cellular CD4-chemokine (CCR5/CXCR4) receptor complex. In this study, for the first time, the HIV-2 A-subtype gp125(C2-V3-C3) mutations and their tropism association were characterized by analyzing 149 HIV-2 sequences from the Los Alamos database. The analysis has strengthened the importance of...

Read the complete abstract on PubMed

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Share to Amino Acid Motifs
Share to env Gene Products, Human Immunodeficiency Virus

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to HIV Infections

Share to Receptors, CCR5

Share to Receptors, CXCR4

Share to Receptors, Virus

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Source

Identifiers

PMID: 21814863
DOI: 10.1007/s00705-011-1075-z

Genes

CCR5
CXCR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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