Article
Prediction of the risk of comorbid alcoholism in schizophrenia by interaction of common genetic variants in the corticotropin-releasing factor system.
Archives of general psychiatry - 1 Dec 2011
Ribbe Katja, Ackermann Verena, Schwitulla Judith, Begemann Martin, Papiol Sergi, Grube Sabrina, Sperling Swetlana, Friedrichs Heidi, Jahn Olaf, Sillaber Inge, Gefeller Olaf, Krampe Henning, Ehrenreich Hannelore
Abstract excerpt
CONTEXT: Stress plays a major role in the development of comorbid alcohol use disorder (AUD). In turn, AUD worsens the outcome of psychiatric patients with respect to global disease severity, social situation, and socioeconomic burden. Prediction of persons at risk for AUD is crucial for future preventive and therapeutic strategies. OBJECTIVE: To investigate whether genetic variants of the corticotropin-releasing...
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