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Article

Variation at the rat Crhr1 locus and sensitivity to relapse into alcohol seeking induced by environmental stress.

Proceedings of the National Academy of Sciences of the United States of America - 10 Oct 2006

Hansson A C, Cippitelli A, Sommer W H, Fedeli A, Björk K, Soverchia L, Terasmaa A, Massi M, Heilig M, Ciccocioppo R

Abstract excerpt

Alcoholism is a chronic relapsing disorder with substantial heritability. Uncovering gene-environment interactions underlying this disease process can aid identification of novel treatment targets. Here, we found a lowered threshold for stress-induced reinstatement of alcohol seeking in Marchigian-Sardinian Preferring (msP) rats genetically selected for high alcohol preference. In situ hybridization for a panel...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to CRF Receptor, Type 1

Share to Rats, Mutant Strains

Share to Rats, Wistar

Share to Receptors, Corticotropin-Releasing Hormone

Share to Recurrence

Share to Stress, Physiological

Source

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Identifiers

PMID: 17015825
DOI: 10.1073/pnas.0604419103
PMCID: PMC1622806

Genes

CRH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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