Article
The CRHR1 gene, trauma exposure, and alcoholism risk: a test of G × E effects.
Genes, brain, and behavior - 1 Jun 2013
Ray L A, Sehl M, Bujarski S, Hutchison K, Blaine S, Enoch M-A
Abstract excerpt
The corticotropin-releasing hormone type I receptor (CRHR1) gene has been implicated in the liability for neuropsychiatric disorders, particularly under conditions of stress. On the basis of the hypothesized effects of CRHR1 variation on stress reactivity, measures of adulthood traumatic stress exposure were analyzed for their interaction with CRHR1 haplotypes and single-nucleotide polymorphisms (SNPs) in...
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