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Article

A mutant of Escherichia coli defective in the first step of endotoxin biosynthesis.

The Journal of biological chemistry - 15 Apr 1990

Galloway S M, Raetz C R

Abstract excerpt

Using localized mutagenesis of whole cells, we have isolated a temperature-sensitive UDP-N-acetylglucosamine acyltransferase mutant of Escherichia coli that loses all detectable acyltransferase activity and quickly dies after a shift from 30 to 42 degrees C. Acyltransferase activity and temperatu...

Topics

Acyltransferases
Escherichia coli
Genes, Bacterial
Genotype
Kinetics
Lipid A
Magnetic Resonance Spectroscopy
Mass Spectrometry
Mutation
Plasmids

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 2180947

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-2180947-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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