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Article

Site-specific acylation changes in the lipid A of Escherichia coli lpxL mutants grown at high temperatures.

Innate immunity - 1 Apr 2014

Schilling Birgit, Hunt Jason, Gibson Bradford W, Apicella Michael A

Abstract excerpt

LPS is a major component of the outer membrane of Gram-negative bacteria. The lipid A region of LPS mediates stimulation of the immune system. In E. coli, the gene (formerly htrB) codes for a late lauroyltransferase (LpxL) in lipid A biosynthesis. E. coli lpxL mutants have been described previously with impaired growth above 33°C in rich media. However, we were able to grow lpxL mutants at 30°C, 37°C and 42°C,...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23812252
DOI: 10.1177/1753425913490534
PMCID: PMC3983921

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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