Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A triple mutant of Escherichia coli lacking secondary acyl chains on lipid A.

The Journal of biological chemistry - 19 Apr 2002

Vorachek-Warren Mara K, Ramirez Suzanne, Cotter Robert J, Raetz Christian R H

Abstract excerpt

All possible combinations of insertion mutations in the three genes encoding the acyl carrier protein-dependent late acyltransferases of lipid A biosynthesis, designated lpxL(htrB), lpxM(msbB), and lpxP, were generated in Escherichia coli K12 W3110. Mutants defective in lpxM synthesize penta-acylated lipid A molecules and grow normally. Strains lacking lpxP fail to incorporate palmitoleate into their lipid A at...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acyltransferases
Share to Carbohydrate Sequence
Share to Cell Division

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cell Membrane

Share to Escherichia coli Proteins

Share to Lipid A

Share to Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

Share to Temperature

Source

Identifiers

PMID: 11830595
DOI: 10.1074/jbc.M200409200

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A triple mutant of Escherichia coli lacking secondary acyl chains on lipid A.PMID 11830595Read ↗

Replacement of lipopolysaccharide with free lipid A molecules in Escherichia coli mutants lacking all core sugars.Semantic proximity Read ↗

Escherichia coli K-12 Suppressor-free Mutants Lacking Early Glycosyltransferases and Late Acyltransferases: minimal lipopolysaccharide structure and induction of envelope stress response.Semantic proximity Read ↗

The LpxL acyltransferase is required for normal growth and penta-acylation of lipid A in Burkholderia cenocepacia.Semantic proximity Read ↗

Site-specific acylation changes in the lipid A of Escherichia coli lpxL mutants grown at high temperatures.Semantic proximity Read ↗

An Escherichia coli mutant lacking the cold shock-induced palmitoleoyltransferase of lipid A biosynthesis: absence of unsaturated acyl chains and antibiotic hypersensitivity at 12 degrees C.Semantic proximity Read ↗

Identification of a broad family of lipid A late acyltransferases with non-canonical substrate specificity.Semantic proximity Read ↗

Identification of two late acyltransferase genes responsible for lipid A biosynthesis in Moraxella catarrhalis.Semantic proximity Read ↗

pmrA(Con) confers pmrHFIJKL-dependent EGTA and polymyxin resistance on msbB Salmonella by decorating lipid A with phosphoethanolamine.Semantic proximity Read ↗

Modification of lipid A structure and activity by the introduction of palmitoyltransferase gene to the acyltransferase-knockout mutant of Escherichia coli.Semantic proximity Read ↗

Outer membrane permeability barrier in Escherichia coli mutants that are defective in the late acyltransferases of lipid A biosynthesis.Semantic proximity Read ↗

A divergent Pseudomonas aeruginosa palmitoyltransferase essential for cystic fibrosis-specific lipid A.Semantic proximity Read ↗

Deciphering the unusual acylation pattern of Helicobacter pylori lipid A.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.