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Article

Construction and characterization of an Escherichia coli mutant producing Kdo₂-lipid A.

Marine drugs - 13 Mar 2014

Wang Jianli, Ma Wenjian, Wang Zhou, Li Ye, Wang Xiaoyuan

Abstract excerpt

3-deoxy-D-manno-oct-2-ulosonic acid (Kdo)₂-lipid A is the conserved structure domain of lipopolysaccharide found in most Gram-negative bacteria, and it is believed to stimulate the innate immune system through the TLR4/MD2 complex. Therefore, Kdo₂-lipid A is an important stimulator for studying the mechanism of the innate immune system and for developing bacterial vaccine adjuvants. Kdo₂-lipid A has not been...

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Source

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Identifiers

PMID: 24633251
DOI: 10.3390/md12031495
PMCID: PMC3967223

Genes

SDS
TLR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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