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Article

Identification of novel genetic susceptibility loci in African American lupus patients in a candidate gene association study.

Arthritis and rheumatism - 1 Nov 2011

Sánchez Elena, Comeau Mary E, Freedman Barry I, Kelly Jennifer A, Kaufman Kenneth M, Langefeld Carl D, Brown Elizabeth E, Alarcón Graciela S, Kimberly Robert P, Edberg Jeffrey C, Ramsey-Goldman Rosalind, Petri Michelle, Reveille John D, Vilá Luis M, Merrill Joan T, Tsao Betty P, Kamen Diane L, Gilkeson Gary S, James Judith A, Vyse Timothy J, Gaffney Patrick M, Jacob Chaim O, Niewold Timothy B, Richardson Bruce C, Harley John B, Alarcón-Riquelme Marta E, Sawalha Amr H

Abstract excerpt

OBJECTIVE: Candidate gene and genome-wide association studies have identified several disease susceptibility loci in lupus patients. These studies have largely been performed in lupus patients who are Asian or of European ancestry. This study was undertaken to examine whether some of these same susceptibility loci increase lupus risk in African American individuals. METHODS: Single-nucleotide polymorphisms...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 21792837
DOI: 10.1002/art.30563
PMCID: PMC3205224

Genes

ITGAM
MSH5
BLK
CFB
CTLA4
STAT4
TNFSF4
IRAK1
MBL2
MECP2
PDCD1
PTPN22
PXK

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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