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Article

MHC region and risk of systemic lupus erythematosus in African American women.

Human genetics - 1 Dec 2011

Ruiz-Narvaez Edward A, Fraser Patricia A, Palmer Julie R, Cupples L Adrienne, Reich David, Wang Ying A, Rioux John D, Rosenberg Lynn

Abstract excerpt

The major histocompatibility complex (MHC) on chromosome 6p21 is a key contributor to the genetic basis of systemic lupus erythematosus (SLE). Although SLE affects African Americans disproportionately compared to European Americans, there has been no comprehensive analysis of the MHC region in relationship to SLE in African Americans. We conducted a screening of the MHC region for 1,536 single nucleotide...

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Identifiers

PMID: 21695597
DOI: 10.1007/s00439-011-1045-2
PMCID: PMC3215804

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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