Article
Ethnic specificity of lupus-associated loci identified in a genome-wide association study in Korean women.
Annals of the rheumatic diseases - 1 Jun 2014
Lee Hye-Soon, Kim Taehyeung, Bang So Young, Na Young Ji, Kim Il, Kim Kwangwoo, Kim Jae-Hoon, Chung Yeun-Jun, Shin Hyoung Doo, Kang Young Mo, Shim Seung-Cheol, Suh Chang-Hee, Park Yong-Beom, Kim Jong-Sung, Kang Changwon, Bae Sang-Cheol
Abstract excerpt
OBJECTIVES: To identify novel genetic candidates for systemic lupus erythematosus (SLE) in the Korean population, and to validate the risk loci for SLE identified in previous genome-wide association studies (GWAS). METHODS: We performed a GWAS in 400 Korean female SLE patients and 445 controls. Selected single-nucleotide polymorphisms (SNP) were then replicated in an independent cohort of 385 SLE patients and 583...
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