Article
Multiple molecular alterations in mouse lung tumors.
Molecular carcinogenesis - 1 Jan 1992
Re F C, Manenti G, Borrello M G, Colombo M P, Fisher J H, Pierotti M A, Della Porta G, Dragani T A
Abstract excerpt
Twenty-five mouse lung tumors induced by a single urethan treatment in female A/J, BALB/c, and (A/J x C3H/He)F1 (AC3) mice were analyzed for the presence of mutations at codon 61 of the Ki-ras gene and for the expression of the surfactant protein A (SP-A), retinoblastoma (Rb), growth arrest-specific-3 (gas-3), p53, c-myc, and thymidylate synthase (TS) genes. Ki-ras codon 61 mutations were detected in 22 of 25...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
