Article
Multiple molecular alterations in mouse lung tumors.
Molecular carcinogenesis - 1 Jan 1992
Re F C, Manenti G, Borrello M G, Colombo M P, Fisher J H, Pierotti M A, Della Porta G, Dragani T A
Abstract excerpt
Twenty-five mouse lung tumors induced by a single urethan treatment in female A/J, BALB/c, and (A/J x C3H/He)F1 (AC3) mice were analyzed for the presence of mutations at codon 61 of the Ki-ras gene and for the expression of the surfactant protein A (SP-A), retinoblastoma (Rb), growth arrest-speci...
Topics
- Animals
- Female
- Gene Expression Regulation, Neoplastic
- Genes, Retinoblastoma
- Genes, myc
- Genes, ras
- Lung Neoplasms
- Mice
- Mice, Inbred A
- Mice, Inbred BALB C
- Mice, Inbred C3H
- Mutation
- Thymidylate Synthase
- Urethane