Article
Ki-ras activation and expression in transformed mouse lung cell lines.
Molecular carcinogenesis - 1 Jan 1990
Pan Y H, Nuzum E O, Hanson L A, Beer D G
Abstract excerpt
The Ki-ras proto-oncogene is activated by specific point mutations and is the transforming gene often identified in rodent and human lung tumors. An in vitro model to aid in the study of the consequences of Ki-ras activation and expression in mouse lung is needed. Accordingly, we have examined cell lines derived from chemically induced mouse lung tumors as well as spontaneous transformants of untreated mouse lung...
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