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Article

Evidence for the involvement of the glucocorticoid receptor gene in bipolar disorder in an isolated northern Swedish population.

Bipolar disorders - 1 Jan 2000

Ceulemans Shana, De Zutter Sonia, Heyrman Lien, Norrback Karl-Fredrik, Nordin Annelie, Nilsson Lars-Göran, Adolfsson Rolf, Del-Favero Jurgen, Claes Stephan

Abstract excerpt

OBJECTIVES: Dysfunction of the hypothalamus-pituitary-adrenal (HPA) axis is one of the most consistent findings in the pathophysiology of mood disorders. The potential role of genes related to HPA axis function has been investigated extensively in major depression. However, in bipolar disorder (BPD) such studies are scarce. We performed a systematic HapMap-based association study of six genes crucial for HPA axis...

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Source

Identifiers

PMID: 22085474
DOI: 10.1111/j.1399-5618.2011.00960.x

Genes

CRH
FKBP5

Provenance

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Evidence for the involvement of the glucocorticoid receptor gene in bipolar disorder in an isolated northern Swedish population.PMID 22085474Read ↗

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