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Article

MDM2 SNP309 polymorphism and breast cancer risk: a meta-analysis.

Molecular biology reports - 1 Apr 2012

Zhao Erjiang, Cui Dan, Yuan Ling, Lu Weiquan

Abstract excerpt

The mouse double minute 2 (MDM2) gene encodes a phosphoprotein that interacts with P53 and negatively regulates its activity. SNP309 polymorphism (T-G) in the promoter of MDM2 gene has been reported to be associated with enhanced MDM2 expression and tumor development. Many published studies have evaluated the association between MDM2 SNP309 polymorphism and breast cancer risk. However, the results were...

Topics

Animals
Breast Neoplasms
Case-Control Studies
Female
Genetic Predisposition to Disease
Humans
Mice
Odds Ratio
Polymorphism, Single Nucleotide
Proto-Oncogene Proteins c-mdm2
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 21725850
DOI: 10.1007/s11033-011-1119-1

Genes

MDM2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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