Article
MDM2 SNP309 polymorphism and breast cancer risk: a meta-analysis.
Molecular biology reports - 1 Apr 2012
Zhao Erjiang, Cui Dan, Yuan Ling, Lu Weiquan
Abstract excerpt
The mouse double minute 2 (MDM2) gene encodes a phosphoprotein that interacts with P53 and negatively regulates its activity. SNP309 polymorphism (T-G) in the promoter of MDM2 gene has been reported to be associated with enhanced MDM2 expression and tumor development. Many published studies have evaluated the association between MDM2 SNP309 polymorphism and breast cancer risk. However, the results were...
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