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Association of the MDM2 SNP285 Polymorphism with Cancer Susceptibility: A Meta-Analysis.

Disease markers - 1 Jan 2016

Wang Ping, Wang Meilin, Li Sanqiang, Ma Lingjun, Xi Shoumin, He Jing

Abstract excerpt

The mouse double minute 2 (MDM2) gene encodes a negative regulator for p53, and the polymorphism SNP285 in the promoter region of MDM2 gene has been implicated in cancer risk, but individual published studies had inconclusive results. Therefore, we performed this meta-analysis to obtain a more precise estimation between MDM2 SNP285 polymorphism and risk of cancer. A systematic literature search was performed...

Topics

Carcinoma
Gene Frequency
Heterozygote
Humans
Polymorphism, Single Nucleotide
Proto-Oncogene Proteins c-mdm2

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 27890964
DOI: 10.1155/2016/4585484
PMCID: PMC5116512

Genes

MDM2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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Association of the MDM2 SNP285 Polymorphism with Cancer Susceptibility: A Meta-Analysis.PMID 27890964Read ↗

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