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Differential effects of MDM2 SNP309 polymorphism on breast cancer risk along with race: a meta-analysis.

Breast cancer research and treatment - 1 Feb 2010

Economopoulos Konstantinos P, Sergentanis Theodoros N

Abstract excerpt

MDM2 SNP309 is a single nucleotide T > G polymorphism present in intron 1 of the MDM2 gene. A variety of case-control studies have been published evaluating the association between MDM2 SNP309 and breast cancer risk. However, the published studies, as well as the subsequent meta-analyses, have yielded contradictory results. This meta-analysis aims to examine whether MDM SNP309 polymorphism may exert a...

Topics

Breast Neoplasms
Female
Genetic Predisposition to Disease
Genotype
Humans
Polymorphism, Single Nucleotide
Proto-Oncogene Proteins c-mdm2
Racial Groups
Risk Factors

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 19590949
DOI: 10.1007/s10549-009-0467-1

Genes

MDM2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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Differential effects of MDM2 SNP309 polymorphism on breast cancer risk along with race: a meta-analysis.PMID 19590949Read ↗

MDM2 SNP309 polymorphism and breast cancer risk: a meta-analysis.Semantic proximity Read ↗

Significant Association of the MDM2 T309G Polymorphism with Breast Cancer Risk in a Turkish PopulationSemantic proximity Read ↗

MDM2 SNP309 contributes to tumor susceptibility: a meta-analysis.Semantic proximity Read ↗

Individual and combined effects of MDM2 SNP309 and TP53 Arg72Pro on breast cancer risk: an updated meta-analysis.Semantic proximity Read ↗

The MDM2 SNP309T>G polymorphism increases bladder cancer risk among Caucasians: a meta-analysis.Semantic proximity Read ↗

Association of MDM2 SNP309 variation with lung cancer risk: evidence from 7196 cases and 8456 controls.Semantic proximity Read ↗

MDM2 SNP309 variation increases cervical cancer risk among Asians.Semantic proximity Read ↗

Involvement of p53 R72P polymorphism in the association of MDM2-SNP309 with breast cancer.Semantic proximity Read ↗

An updated meta-analysis on the association of MDM2 SNP309 polymorphism with colorectal cancer risk.Semantic proximity Read ↗

Results based on 124 cases of breast cancer and 97 controls from Taiwan suggest that the single nucleotide polymorphism (SNP309) in the MDM2 gene promoter is associated with earlier onset and increased risk of breast cancer.Semantic proximity Read ↗

MDM2 SNP309 variation contributes to leukemia risk: meta-analyses based on 7259 subjects.Semantic proximity Read ↗

MDM2 SNP309 polymorphism contributes to endometrial cancer susceptibility: evidence from a meta-analysis.Semantic proximity Read ↗

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