Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

MDM2 SNP309 polymorphism and colorectal cancer risk: a meta-analysis.

DNA and cell biology - 1 Mar 2012

Cao Xiangming, Zhang Tingrong, Zhao Zhen, Zhao Tao

Abstract excerpt

MDM2 is a phosphoprotein that interacts with p53 and inhibits its activity. Recently, a T to G substitution (SNP309) in the promoter of MDM2 was identified and associated with increased MDM2 expression and a significantly earlier age of onset of several tumors, including colorectal cancer. Several studies evaluated the association between SNP309 and colorectal cancer risk in diverse populations. However, the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Colorectal Neoplasms
Share to MDM2 gene
Share to Polymorphism, Single Nucleotide

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Proto-Oncogene Proteins c-mdm2

Share to Risk Factors

Source

Identifiers

PMID: 21770737
DOI: 10.1089/dna.2011.1338

Genes

MDM2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

MDM2 SNP309 polymorphism and colorectal cancer risk: a meta-analysis.PMID 21770737Read ↗

An updated meta-analysis on the association of MDM2 SNP309 polymorphism with colorectal cancer risk.Semantic proximity Read ↗

Current evidence on the relationship between SNP309 polymorphism in the MDM2 gene and colorectal cancer risk.Semantic proximity Read ↗

MDM2 SNP309 polymorphism is associated with colorectal cancer risk.Semantic proximity Read ↗

MDM2 SNP309 contributes to tumor susceptibility: a meta-analysis.Semantic proximity Read ↗

MDM2 SNP309 polymorphism and breast cancer risk: a meta-analysis.Semantic proximity Read ↗

MDM2 309 T/G polymorphism is associated with colorectal cancer risk especially in Asians: a meta-analysis.Semantic proximity Read ↗

MDM2 SNP309 is associated with endometrial cancer susceptibility: a meta-analysis.Semantic proximity Read ↗

MDM2 SNP309 rs2279744 polymorphism and gastric cancer risk: a meta-analysis.Semantic proximity Read ↗

MDM2 SNP309 polymorphism contributes to endometrial cancer susceptibility: evidence from a meta-analysis.Semantic proximity Read ↗

MDM2 SNP309, gene-gene interaction, and tumor susceptibility: an updated meta-analysis.Semantic proximity Read ↗

MDM2 promoter polymorphism SNP309 contributes to tumor susceptibility: evidence from 21 case-control studies.Semantic proximity Read ↗

Impact of MDM2 polymorphism: increased risk of developing colorectal cancer and a poor prognosis in the Tunisian population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.