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Article

Matrix Gla protein polymorphism, but not concentrations, is associated with radiographic hand osteoarthritis.

The Journal of rheumatology - 1 Sept 2011

Misra Devyani, Booth Sarah L, Crosier Micheal D, Ordovas Jose M, Felson David T, Neogi Tuhina

Abstract excerpt

OBJECTIVE: Factors associated with mineralization and osteophyte formation in osteoarthritis (OA) are incompletely understood. Genetic polymorphisms of matrix Gla protein (MGP), a mineralization inhibitor, have been associated clinically with conditions of abnormal calcification. We therefore evaluated the relationship of MGP concentrations and polymorphisms at the MGP locus to hand OA. METHODS: Ours was an...

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Identifiers

PMID: 21724703
DOI: 10.3899/jrheum.100985
PMCID: PMC3200118

Genes

MGP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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