Article
Polymorphisms of the human matrix gla protein (MGP) gene, vascular calcification, and myocardial infarction.
Arteriosclerosis, thrombosis, and vascular biology - 1 Nov 2000
Herrmann S M, Whatling C, Brand E, Nicaud V, Gariepy J, Simon A, Evans A, Ruidavets J B, Arveiler D, Luc G, Tiret L, Henney A, Cambien F
Abstract excerpt
The matrix Gla protein (MGP) is an important inhibitor of vessel and cartilage calcification that is strongly expressed in human calcified, atherosclerotic plaques and could modulate plaque calcification and coronary heart disease risk. Using a genetic approach, we explored this possibility by identifying polymorphisms of the MGP gene and testing their possible association with myocardial infarction (MI) and...
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