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Article

Matrix Gla protein is an independent predictor of both intimal and medial vascular calcification in chronic kidney disease.

Scientific reports - 20 Apr 2020

Jaminon Armand M G, Dai Lu, Qureshi Abdul Rashid, Evenepoel Pieter, Ripsweden Jonaz, Söderberg Magnus, Witasp Anna, Olauson Hannes, Schurgers Leon J, Stenvinkel Peter

Abstract excerpt

Matrix Gla protein (MGP) is a potent inhibitor of vascular calcification (VC) and requires carboxylation by vitamin K to exert calcification inhibition. Chronic kidney disease (CKD) patients undergo early vascular aging often involving extensive VC. The present cross-sectional study investigated the association between circulating dp-ucMGP levels, MGP expression in vascular tissue and MGP polymorphisms. In 141...

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Identifiers

PMID: 32313061
DOI: 10.1038/s41598-020-63013-8
PMCID: PMC7171129

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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