Article
Matrix Gla protein polymorphisms are associated with coronary artery calcification in men.
Journal of nutritional science and vitaminology - 1 Feb 2009
Crosier Michael D, Booth Sarah L, Peter Inga, Dawson-Hughes Bess, Price Paul A, O'Donnell Christopher J, Hoffmann Udo, Williamson Matthew K, Ordovas Jose M
Abstract excerpt
Matrix Gla protein (MGP) is a key regulator of vascular calcification. Genetic variation at the MGP locus could modulate the development of coronary artery calcification (CAC). Our aim was to examine the cross-sectional association between MGP single nucleotide polymorphisms (SNPs) [rs1800802 (T-138C), rs1800801 (G-7A), and rs4236 (Ala102Thr)] and CAC. CAC was measured by multidetector computed tomography (MDCT),...
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