Article
Genetic association analysis of Osteopontin and Matrix Gla Protein genes polymorphisms with primary knee osteoarthritis in Mexican population.
Clinical rheumatology - 1 Jan 2019
Borgonio-Cuadra Verónica Marusa, González-Huerta Norma Celia, Rojas-Toledo Emma Xochitl, Morales-Hernández Eugenio, Pérez-Hernández Nonanzit, Rodríguez-Pérez José Manuel, Tovilla-Zárate Carlos Alfonso, González-Castro Thelma Beatriz, Hernández-Díaz Yazmín, López-Narváez María Lilia, Miranda-Duarte Antonio
Abstract excerpt
Primary osteoarthritis (OA) is a complex entity in which several loci related to different molecular pathways or classes of molecules are associated with its development as demonstrated through genetic association studies. Genes involved in bone formation and mineralization, such as osteopontin (OPN) and Matrix Gla protein (MGP), could also be related with OA. The aim of this study was to evaluate the association...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
