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Article

Matrix gla protein gene polymorphism is associated with increased coronary artery calcification progression.

Arteriosclerosis, thrombosis, and vascular biology - 1 Mar 2013

Cassidy-Bushrow Andrea E, Bielak Lawrence F, Levin Albert M, Sheedy Patrick F, Turner Stephen T, Boerwinkle Eric, Lin Xihong, Kardia Sharon L R, Peyser Patricia A

Abstract excerpt

OBJECTIVE: Matrix gla protein (MGP) inhibits arterial and cartilaginous calcification. A threonine to alanine (Thr83Ala) polymorphism (codon 83) in MGP is associated with myocardial infarction and femoral artery calcification. We examined the association of the MGP Thr83Ala polymorphism with quantity and progression of coronary artery calcification (CAC), a noninvasive measure of subclinical coronary...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23307874
DOI: 10.1161/ATVBAHA.112.300491
PMCID: PMC3586431

Genes

MGP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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