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Article

Association of matrix Gla protein gene functional polymorphisms with loss of bone mineral density and progression of aortic calcification.

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA - 1 Apr 2014

Tuñón-Le Poultel D, Cannata-Andía J B, Román-García P, Díaz-López J B, Coto E, Gómez C, Naves-Díaz M, Rodríguez I

Abstract excerpt

UNLABELLED: Two matrix Gla protein (MGP) polymorphisms were associated with progression of aortic calcification and femoral neck bone loss in men. All these findings were also functionally corroborated in two vascular and bone in vitro systems indicating that MGP genetic variations can be partly responsible of higher risk of bone loss and vascular calcification. INTRODUCTION: MGP plays an important role in bone...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 24281054
DOI: 10.1007/s00198-013-2577-1

Genes

MGP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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