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Expression analysis of the osteoarthritis genetic susceptibility mapping to the matrix Gla protein gene MGP

18 Jun 2019

Abstract excerpt

BACKGROUND: Osteoarthritis (OA) is a common disease of older individuals that impacts detrimentally on the quality and the length of life. It is characterised by the painful loss of articular cartilage and is polygenic and multifactorial. Genome-wide association scans have highlighted over 90 osteoarthritis genetic signals, some of which reside within or close to highly plausible candidate genes. An example is an...

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PMID: 31215457
DOI: 10.1186/s13075-019-1934-7

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