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Article

Comparison of allelic discrimination by dHPLC, HRM, and TaqMan in the detection of BRAF mutation V600E.

The Journal of molecular diagnostics : JMD - 1 Sept 2011

Carbonell Pablo, Turpin María C, Torres-Moreno Daniel, Molina-Martínez Irene, García-Solano José, Perez-Guillermo Miguel, Conesa-Zamora Pablo

Abstract excerpt

The V600E mutation in the BRAF oncogene is associated with colorectal carcinomas, with mismatch-repair deficiency and, recently, with nonresponse to epidermal growth factor receptor inhibitor therapy. The use of reliable techniques for its detection is important. The aim of our study was to compare the performance characteristics in V600E detection of denaturing high-performance liquid chromatography (dHPLC) and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Proto-Oncogene Proteins B-raf

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Source

Open in PubMed Open full text

Identifiers

PMID: 21708284
DOI: 10.1016/j.jmoldx.2011.03.009
PMCID: PMC3157612

Genes

BRAF

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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