Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Assessment of DHPLC usefulness in the genotyping of GSTP1 exon 5 SNP: comparison to the PCR-RFLP method.

Journal of biochemical and biophysical methods - 31 May 2004

Abbas Ahmed, Lepelley Maud, Lechevrel Mathilde, Sichel François

Abstract excerpt

Single-nucleotide polymorphism (SNP) analysis can be performed by several methods such as PCR-RFLP, real time PCR and mass spectrometry. Denaturating High Pressure Liquid Chromatography (DHPLC) analysis allows the detection of DNA mutations in heteroduplex samples. GSTP1 exon 5 gene presents a single-nucleotide polymorphism (a to g) that results into an amino-acid substitution (Ile to Val). Ile and Val variants...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acyltransferases
Share to Chromatography, High Pressure Liquid

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Nucleic Acid Denaturation

Share to Polymerase Chain Reaction

Share to Polymorphism, Restriction Fragment Length

Share to Temperature

Source

Identifiers

PMID: 15163523
DOI: 10.1016/j.jbbm.2003.12.008

Genes

GSTP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Assessment of DHPLC usefulness in the genotyping of GSTP1 exon 5 SNP: comparison to the PCR-RFLP method.PMID 15163523Read ↗

The use of denaturing high-performance liquid chromatography (DHPLC) for the analysis of genetic variations: impact for diagnostics and pharmacogenetics.Semantic proximity Read ↗

Analysis of human glutathione S-transferase alpha 1 (hGSTA1) gene promoter polymorphism using denaturing high performance liquid chromatography (DHPLC).Semantic proximity Read ↗

Denaturing high-performance liquid chromatography for mutation detection and genotyping.Semantic proximity Read ↗

Denaturing HPLC for mutation screening.Semantic proximity Read ↗

Evaluation of denaturing high performance liquid chromatography for the mutational analysis of the MEN1 gene.Semantic proximity Read ↗

[Comparison of denaturing high performance liquid chromatography with direct sequencing in the detection of single nucleotide polymorphism].Semantic proximity Read ↗

Cheap, accurate and rapid allele frequency estimation of single nucleotide polymorphisms by primer extension and DHPLC in DNA pools.Semantic proximity Read ↗

Identification of specific BRCA1 and BRCA2 variants by DHPLCSemantic proximity Read ↗

Denaturing high-performance liquid chromatography for mutation detection and genotyping.Semantic proximity Read ↗

Denaturing high-performance liquid chromatography in the detection of ABCA1 gene mutations in familial HDL deficiency.Semantic proximity Read ↗

Reliability of DHPLC in mutational screening of beta-globin (HBB) alleles.Semantic proximity Read ↗

A versatile denaturing HPLC approach for human beta-globin gene mutation screening.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.