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Article

Signature-based analysis of MET proto-oncogene mutations using DHPLC.

Human mutation - 1 Jan 2000

Nickerson M L, Weirich G, Zbar B, Schmidt L S

Abstract excerpt

Research tools which improve mutation detection, SNP discovery, and allele characterization will facilitate studies of cancer, inherited disease, and genomic evolution. Denaturing High-Performance Liquid Chromatography (DHPLC) is a recently developed methodology for detection of heteroduplexes formed in DNA samples containing mismatches between wild type and mutant strands. In an effort to develop a rapid,...

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Share to Carcinoma, Renal Cell
Share to Chromatography, High Pressure Liquid
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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Electrophoresis, Agar Gel

Share to Heteroduplex Analysis

Share to Polymorphism, Single-Stranded Conformational

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Share to Proto-Oncogene Proteins c-met

Source

Identifiers

PMID: 10874308
DOI: 10.1002/1098-1004(200007)16:1<68::AID-HUMU12>3.0.CO;2-U

Genes

MET

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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