Article
Arp2/3 promotes junction formation and maintenance in the Caenorhabditis elegans intestine by regulating membrane association of apical proteins.
Molecular biology of the cell - 15 Aug 2011
Bernadskaya Yelena Y, Patel Falshruti B, Hsu Hsiao-Ting, Soto Martha C
Abstract excerpt
It has been proposed that Arp2/3, which promotes nucleation of branched actin, is needed for epithelial junction initiation but is less important as junctions mature. We focus here on how Arp2/3 contributes to the Caenorhabditis elegans intestinal epithelium and find important roles for Arp2/3 in the maturation and maintenance of junctions in embryos and adults. Electron microscope studies show that embryos...
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