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Article

A role for the centrosome and PAR-3 in the hand-off of MTOC function during epithelial polarization.

Current biology : CB - 10 Apr 2012

Feldman Jessica L, Priess James R

Abstract excerpt

BACKGROUND: The centrosome is the major microtubule organizing center (MTOC) in dividing cells and in many postmitotic, differentiated cells. In other cell types, however, MTOC function is reassigned from the centrosome to noncentrosomal sites. Here, we analyze how MTOC function is reassigned to the apical membrane of C. elegans intestinal cells. RESULTS: After the terminal intestinal cell division, the...

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Identifiers

PMID: 22425160
DOI: 10.1016/j.cub.2012.02.044
PMCID: PMC3409831

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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