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Article

Caenorhabditis elegans screen reveals role of PAR-5 in RAB-11-recycling endosome positioning and apicobasal cell polarity.

Nature cell biology - 27 May 2012

Winter Julia Franziska, Höpfner Sebastian, Korn Kerstin, Farnung Benjamin O, Bradshaw Charles R, Marsico Giovanni, Volkmer Michael, Habermann Bianca, Zerial Marino

Abstract excerpt

Apically enriched Rab11-positive recycling endosomes (Rab11-REs) are important for establishing and maintaining epithelial polarity. Yet, little is known about the molecules controlling trafficking of Rab11-REs in an epithelium in vivo. Here, we report a genome-wide, image-based RNA interference screen for regulators of Rab11-RE positioning and transport of an apical membrane protein (PEPT-1) in C. elegans...

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PMID: 22634595
DOI: 10.1038/ncb2508

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RHO

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Caenorhabditis elegans screen reveals role of PAR-5 in RAB-11-recycling endosome positioning and apicobasal cell polarity.PMID 22634595Read ↗

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