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Article

Ezrin is essential for epithelial organization and villus morphogenesis in the developing intestine.

Developmental cell - 1 Jun 2004

Saotome Ichiko, Curto Marcello, McClatchey Andrea I

Abstract excerpt

Ezrin, Radixin, and Moesin (the ERM proteins) supply regulated linkage between membrane proteins and the actin cytoskeleton. The study of mammalian ERM proteins has been hampered by presumed functional overlap. We have found that Ezrin, the only ERM detected in epithelial cells of the developing intestine, provides an essential role in configuring the mouse intestinal epithelium. Surprisingly, Ezrin is not...

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Identifiers

PMID: 15177033
DOI: 10.1016/j.devcel.2004.05.007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Ezrin is essential for epithelial organization and villus morphogenesis in the developing intestine.PMID 15177033Read ↗

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Ezrin Mediates Invasion and Metastasis in Tumorigenesis: A ReviewSemantic proximity Read ↗

A gene family consisting of ezrin, radixin and moesin Its specific localization at actin filament/plasma membrane association sitesSemantic proximity Read ↗

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