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Article

LET-413 is a basolateral protein required for the assembly of adherens junctions in Caenorhabditis elegans.

Nature cell biology - 1 Jul 2000

Legouis R, Gansmuller A, Sookhareea S, Bosher J M, Baillie D L, Labouesse M

Abstract excerpt

Epithelial cells are polarized, with apical and basal compartments demarcated by tight and adherens junctions. Proper establishment of these subapical junctions is critical for normal development and histogenesis. We report the characterization of the gene let-413 which has a critical role in assembling adherens junctions in Caenorhabditis elegans. In let-413 mutants, adherens junctions are abnormal and...

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PMID: 10878806
DOI: 10.1038/35017046

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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