Article
Association analyses confirm five susceptibility loci for systemic lupus erythematosus in the Han Chinese population.
Arthritis research & therapy - 28 Mar 2015
Sheng Yu-jun, Xu Jian-hua, Wu Yong-gui, Zuo Xian-bo, Gao Jin-ping, Lin Yan, Zhu Zheng-wei, Wen Lei-lei, Yang Chao, Liu Lu, Cheng Yu-yan, Chang Yan, Yang Lu-lu, Zhou Fu-sheng, Tang Xian-fa, Zheng Xiao-dong, Yin Xian-yong, Tang Hua-yang, Sun Liang-dan, Cui Yong, Yang Sen, Zhang Xue-jun
Abstract excerpt
INTRODUCTION: Systemic lupus erythematosus (SLE) is a multisystem autoimmune disease. Currently, numerous genetic loci of SLE have been confirmed. Here we try to further explore additional genes contributing to SLE susceptibility in this study. METHODS: Forty nine single nucleotide polymorphisms (SNPs) with moderate-risk for SLE in previous study were genotyped in a large-scale replication study with a total of...
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