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Article

Apolipoprotein E ε2 and functional decline in amnestic mild cognitive impairment and Alzheimer disease.

The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry - 1 Jul 2012

Bonner-Jackson Aaron, Okonkwo Ozioma, Tremont Geoffrey

Abstract excerpt

BACKGROUND: Recent work has demonstrated the potentially protective effects of the apolipoprotein E (APOE) ε2 allele on cognitive functioning in individuals at risk for developing Alzheimer disease. However, little is known regarding the effect of ε2 genotype on rate of change in daily functioning over time. The aim of the current study was to examine the relationship between APOE genotype and change over time in...

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Source

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Identifiers

PMID: 21685781
DOI: 10.1097/JGP.0b013e3182203c32
PMCID: PMC3188382

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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