Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Possible association between ubiquitin-specific peptidase 46 gene and major depressive disorders in the Japanese population.

Journal of affective disorders - 1 Sept 2011

Fukuo Yasuhisa, Kishi Taro, Kushima Itaru, Yoshimura Reiji, Okochi Tomo, Kitajima Tsuyoshi, Matsunaga Shinji, Kawashima Kunihiro, Umene-Nakano Wakako, Naitoh Hiroshi, Inada Toshiya, Nakamura Jun, Ozaki Norio, Iwata Nakao

Abstract excerpt

BACKGROUND: Several investigations have reported that abnormalities in circadian rhythms might be related to the pathophysiology of major depressive disorder (MDD) and the therapeutic response to selective serotonin reuptake inhibitors (SSRIs). Recently, ubiquitin-specific peptidase 46 (USP46), a new molecule related to the circadian clock system, has been described. We conducted a case control study between...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Circadian Clocks
Share to Depressive Disorder, Major

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Endopeptidases

Share to Fluvoxamine

Share to Paroxetine

Share to Psychiatric Status Rating Scales

Share to Selective Serotonin Reuptake Inhibitors

Share to Ubiquitin

Source

Identifiers

PMID: 21663972
DOI: 10.1016/j.jad.2011.04.020

Genes

USP46

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Possible association between ubiquitin-specific peptidase 46 gene and major depressive disorders in the Japanese population.PMID 21663972Read ↗

Association study of ubiquitin-specific peptidase 46 (USP46) with bipolar disorder and schizophrenia in a Japanese population.Semantic proximity Read ↗

SIRT1 gene is associated with major depressive disorder in the Japanese population.Semantic proximity Read ↗

Pharmacogenetic study of serotonin 6 receptor gene with antidepressant response in major depressive disorder in the Japanese population.Semantic proximity Read ↗

CLOCK may predict the response to fluvoxamine treatment in Japanese major depressive disorder patients.Semantic proximity Read ↗

Serotonin 6 receptor gene and mood disorders: case-control study and meta-analysis.Semantic proximity Read ↗

The Sex- and Age-Specific Association of AANAT Gene Polymorphisms With the Risk of Major Depressive Disorder in the Chinese Population.Semantic proximity Read ↗

A neuropeptide Y variant (rs16139) associated with major depressive disorder in replicate samples from Chinese Han population.Semantic proximity Read ↗

Genome-wide association study of SSRI/SNRI-induced sexual dysfunction in a Japanese cohort with major depression.Semantic proximity Read ↗

The role of clock genes in the etiology of Major Depressive Disorder: Special Section on "Translational and Neuroscience Studies in Affective Disorders". Section Editor, Maria Nobile MD, PhD. This Section of JAD focuses on the relevance of translational and neuroscience studies in providing a better understanding of the neural basis of affective disorders. The main aim is to briefly summaries relevant research findings in clinical neuroscience with particular regards to specific innovative topi…Semantic proximity Read ↗

Association analysis of SIGMAR1 with major depressive disorder and SSRI response.Semantic proximity Read ↗

The CLOCK gene and mood disorders: a case-control study and meta-analysis.Semantic proximity Read ↗

Behavioral characteristics of ubiquitin-specific peptidase 46-deficient mice.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.