Article
The CLOCK gene and mood disorders: a case-control study and meta-analysis.
Chronobiology international - 1 Nov 2011
Kishi Taro, Yoshimura Reiji, Fukuo Yasuhisa, Kitajima Tsuyoshi, Okochi Tomo, Matsunaga Shinji, Inada Toshiya, Kunugi Hiroshi, Kato Tadafumi, Yoshikawa Takeo, Ujike Hiroshi, Umene-Nakano Wakako, Nakamura Jun, Ozaki Norio, Serretti Alessandro, Correll Christoph U, Iwata Nakao
Abstract excerpt
The clock gene (CLOCK) is considered to be a good candidate gene for the pathophysiology of mood disorders, including bipolar disorder (BP) and major depressive disorder (MDD). rs1801260 (T3111C) has been detected at position 3111 in the CLOCK mRNA 3' untranslated region, and was reported to be associated with a substantial delay in preferred timing for activity and sleep in a human study. As for function,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.