Article
SIRT1 gene is associated with major depressive disorder in the Japanese population.
Journal of affective disorders - 1 Oct 2010
Kishi Taro, Yoshimura Reiji, Kitajima Tsuyoshi, Okochi Tomo, Okumura Takenori, Tsunoka Tomoko, Yamanouchi Yoshio, Kinoshita Yoko, Kawashima Kunihiro, Fukuo Yasuhisa, Naitoh Hiroshi, Umene-Nakano Wakako, Inada Toshiya, Nakamura Jun, Ozaki Norio, Iwata Nakao
Abstract excerpt
BACKGROUND: Many studies including our previous ones as to PROKR2 and CLOCK have suggested that circadian genes may be involved in the mechanisms of mood disorders and their treatment responses. Also several recent investigations have reported that SIRT1 plays an important role in the circadian s...
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