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Article

Pharmacogenetic study of serotonin 6 receptor gene with antidepressant response in major depressive disorder in the Japanese population.

Human psychopharmacology - 1 Aug 2010

Kishi Taro, Fukuo Yasuhisa, Yoshimura Reiji, Okochi Tomo, Kitajima Tsuyoshi, Naitoh Hiroshi, Umene-Nakano Wakako, Nakamura Jun, Ozaki Norio, Iwata Nakao

Abstract excerpt

OBJECTIVE: Several investigations have suggested that alterations in serotonin 6 (5-HT6) receptors might be associated with the pathophysiology of major depressive disorder (MDD), and that 5-HT6 receptors might be a therapeutic target for serotonin selective reuptake inhibitor (SSRI) in MDD. To evaluate the association between HTR6 and the efficacy of SSRI treatment in Japanese MDD patients, we conducted a...

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Source

Identifiers

PMID: 20737521
DOI: 10.1002/hup.1142

Genes

HTR6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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