Article
Serotonin 6 receptor gene and mood disorders: case-control study and meta-analysis.
Neuroscience research - 1 Jul 2010
Fukuo Yasuhisa, Kishi Taro, Yoshimura Reiji, Kitajima Tsuyoshi, Okochi Tomo, Yamanouchi Yoshio, Kinoshita Yoko, Kawashima Kunihiro, Naitoh Hiroshi, Umene-Nakano Wakako, Inada Toshiya, Kunugi Hiroshi, Kato Tadafumi, Yoshikawa Takeo, Ujike Hiroshi, Nakamura Jun, Ozaki Norio, Iwata Nakao
Abstract excerpt
Several evidence suggests that alterations in serotonin 6 (5-HT6) receptors might be associated with the pathophysiology of mood disorders. Therefore, to evaluate the association between HTR6 and BP and MDD, we conducted a case-control study of Japanese population samples (1007 BP patients, 447 MDD patients and 1753 controls) with five tagging SNPs, including rs1805054 (C267T), in HTR6. In addition, we conducted...
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