Article
Behavioral characteristics of ubiquitin-specific peptidase 46-deficient mice.
PloS one - 1 Jan 2013
Imai Saki, Kano Makoto, Nonoyama Keiko, Ebihara Shizufumi
Abstract excerpt
We have previously identified Usp46, which encodes for ubiquitin-specific peptidase 46, as a quantitative trait gene affecting the immobility time of mice in the tail suspension test (TST) and forced swimming test. The mutation that we identified was a 3-bp deletion coding for lysine (Lys 92), and mice with this mutation (MT mice), as well as Usp46 KO mice exhibited shorter TST immobility times. Behavioral...
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